Lifespan : Why We Age – and Why We Don’t Have To by David A. Sinclair
Lifespan : Why We Age – and Why We Don’t Have To by David A. Sinclair
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Book Summary
Lifespan presents scientist David A. Sinclair’s groundbreaking claim that aging is not an inevitable decline but a condition that can be slowed—and potentially reversed—by addressing what he calls the “information theory of aging.” According to Sinclair, aging occurs because the body’s cells gradually lose their ability to read and use genetic information correctly, leading to damage, disease, and physical deterioration. The book explores scientific advances showing how activating longevity pathways—such as sirtuins, NAD boosters, and calorie restriction mimetics—can restore cellular function and extend healthy lifespan in animals, with promising implications for humans. Sinclair also discusses lifestyle practices that support longevity, including fasting, cold exposure, exercise, plant-rich diets, and reducing stress. Blending cutting-edge genetics, real experiments, and future possibilities, Lifespan argues that aging should be treated as a disease—and that humanity may be on the brink of a revolution where people live longer, healthier lives.
About the Author —
David A. Sinclair is an Australian-American biologist, professor of genetics at Harvard Medical School, and one of the world’s leading researchers on aging and longevity. His work focuses on understanding why we age and how to activate the body’s natural defense systems to extend lifespan. Sinclair is best known for his pioneering research on sirtuins, NAD+, resveratrol, and epigenetic aging, which has influenced both academic science and the biotechnology industry. He has co-founded several biotech companies aimed at developing anti-aging therapies and is a prominent public communicator on the future of health and longevity. Through his scientific achievements, writing, and advocacy, Sinclair has become a central figure in the field of age research, inspiring global interest in the science of extending healthy life.
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